The actress, who plays Sunita Alahan in the ITV soap, has received race hate messages over the last two weeks.
Last week she posted a message on the site saying: "Surprised at the racial abuse and desire to try and hurt people for no reason. I think I'm giving twitter a wee rest..gobsmacked."
But the 44-year-old has now apparently decided to quit the site altogether, telling her 18,467 followers: "Thanks for the banter I've enjoyed my time on twitter. Over and out."
Shobna, who is of indian descent, has campaigned against racism and intolerance and used Twitter to spread information about her campaigns.
She set up an account in support of the Sophie Charity, in honour of Sophie Lancaster, 20, who was murdered in Bacup in 2007.
Steve Huison, who played Eddie Windass in the Street, posted a message saying: "Absolutely disgusted to see that my lovely friend Shobna has been driven off Twitter because of racists. Shame on them."
Julie Hesmondhalgh, 41, who plays Hayley Cropper, in the soap has also received abuse via Twitter.
Julie Tweeted: "Those who just use this to bandy their own hatred and desperation really need to look at themselves."
Manchester Evening News
